Dear Devs, I've been getting crashes + slowdown after 100 population. I suspect the crashes have to do with setting Selenians on fire with a Leyden Rifle. Also, if you look at the Lab, it has -1000 points because if you click multiple times while the game is saving, apparently it will research all the techs 'behind' the first one.
I believe a crash in the particle system has been fixed, which would fix your Selenian / Leyden problems. Oh, boy. Logged as OC-5922.