I bet It's already been mentioned somewhere, but I can't find a thread about it.. Skills with a lot of active abilities produce lists which end up partially out of screen.
I agree that this is a bother. I use the "use larger UI elements" all of the time, and I can't see a lot of skills. I have to disable this feature, then assign spells to slots, then turn it back on. I'd be OK if the position of the skill tree was fixed no matter which spell slot I chose. No need to make it scroll or anything. I know what slot I clicked, and if I mess it up I can just try again. Skills can have up to eight spells, but I can only see three of them in the right-most slot! (I use 1776x1000 windowed mode)