"You've caught an embarrassing and debilitating disease." Any way to cure it (besides waiting)? The wiki doesn't help.
Potion of Purity, or Zodiacal Wand. Occasionally possible by fountain drinking too, but I wouldn't try that method.
Not really worth blowing a Potion of Purity on, if you ask me. Not a bad choice for a Zodiacal Wand use, especially if you have Wand Lore. I typically just ignore it and continue on, it's really not that dangerous of a debuff.