As title says, my dredmor "CTD" without a warning half the times I try to open it from using the game launcher. I play with Steam but no steam cloud nor steam workshop mod is active. Mods from this mod are in, however. I have 54 active mods at the time. And I say this since I'm pretty sure it's the number of mods which destabilize the game: with no one or just few mods active, the game does NEVER CTD from the launcher.