I have started 8 or so run throughs so far and every single one of them has broken at some point, usually on the second or third floor. Just long enough in to be invested in the character. It is incredibly frustrating. The issue is always the same, crashing to desktop when entering the pocket dimension. I have tried the latest hot fixes. Any suggestions as to what I can do? Or at least how to avoid this?
This is an issue with the coding for generating new levels. It has been stated that the next hotfix (10) will probably include the fixes for this. you aren't the only one experiencing this.
I've been having a ridiculous amount of game-breaking bugs, too. I think I'm done until it gets patched up.
I have been avoiding the pocket dimension and have had no problems at all. It's a lot more tedious, but I have just gone back to doing what I did before: leaving a stockpile of items in an empty room near a store and a stairs down. When I leave the level I lug everything down to the next level. Lather, rinse, repeat. I just pretend the pocket dimension doesn't exist.