This seems basic enough that someone else would have reported it by now but I haven't seen it here. Whenever I use Polymorphic Injunction (Wizard Law 2nd skill) on a monster twice the game crashes. Tried it several times on different monsters.
We're on it. Meanwhile if you want to use http://patches.gaslampgames.com/dredmor/dredmor_hotfix_test3.zip, that fixes it. However it's not hooked to Steam so you won't get achievements or cloud syncing.
I'll probably post this bug here. If skill used on water monster(eely and others) the game crashes. Hotfix3 applied.
Here it is, there was another crash on lvl5 when i used that skill on rutabaga. I'm scared of their insane damage. Crashes was on lvl 4 and 5 and save currently on lvl7, i hope this helps.