Was on dungeon level 3, standing next to Brax in his shop. It's time for me to go to bed, so I hit escape, click "Save and Quit" and then watch my character keel over in death just before the game exits. Huh? I go to "load" - and the character just has a "dead in the shop" save file. Is this a known bug?
You didn't happen to have a bad debuff / DOT on you at the time did you? I had a similar issue when I tried 'saving and continuing' during a zoo after getting spammed with spells.