I don't know about you guys, but with the Steam workshop I like to throw in as many mods as I feel like. I mostly skills, because why not? However, for whatever reason my game likes to deselect all the mods on the loading screen periodically, and it's slightly irritating to have to click through all of them again to reenable them. I was thinking a little checkbox at the top to use all the mods, and it could also be unchecked to deactivate all the mods to play vanilla.