The Horadric Lutefisk Cube should play the 'Skol!' sound everytimes you open it for the sheer epicness.
So, I was watching a DoD LP, and noticed that this was one of the quest items that the LPer stumbled across: Possible reference to Canadian poker player Daniel Negreanu?
I found a pair of rings, one called Bangbelunf, the Bringer of Apologies and the second was named Cyrfur, the Magical Breakfast Cereal. It got a laugh out of me.
Steam goofed up whne I was trying to upload a screenshot. I ran into an item just now on a new character and the name was: Achseekol, the Mid-afternoon's Breakfast Cereals
Well I had this one a while ago... Yes, that's a pair of pants with the appelation "the Awkward Sausage".
On a recent playthrough I found a Giant Stone Club with the name, Ulfaas the CEO of Portals. Cave Johnson anyone?
"Alright, this next test involves a bit of time travel. And if you happen to meet your future self on the track, don't look him in the eyes, the lab boys said that will wipe out time, all of it, forwards and back." Cave Johnson. What's interesting, is I didn't know the voice actor for Cave was the same as the actor who played Jonah Jameson in the Spiderman movies. Not only that, but he was also on Law and Order SVU in the beginning seasons.